| Autor: |
Olufunso, Adeoye Bayo, Ayobola, Iyanda Abolape, Michael, Oyerinde Ayodeji, Oyebimpe, Oyeleke Ibukunoluwa, Olayinka, Fadeyi Blessing |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Nigerian Journal of Nutritional Sciences; Vol. 43 No. 2 (2022); 27-32 |
| ISSN: |
0189-0913 |
| Popis: |
Background: Nigeria has the highest prevalence of diabetes in Sub - Saharan Africa. The relative contraindications associated with conventional oral hypoglycemic drugs demand the search for nutraceuticals as ideal alternatives.Objective: In this study, we aimed at elucidating possible antiglycemic properties of Nigerian sweet and bitter honey from Apis Mellifera Andasonii through the pathway of alpha amylase inhibition.Method: The pH of the honey samples was determined using a digital pH meter (pHs-2F, Harris, England). Standard assay methods using 3, 5 - dinitrosalicylic acid (DNSA) was used to analyse alpha amylase activity invitro. The honey concentration which inhibited 50% alpha amylase activity (IC ) was 50 determined using the dose response curve. Data were analysed using student t-test on graph pad prism 6.1.Result: The sweet and bitter honey samples exhibited low pH values of 3.30 and 3.38 respectively. The dose dependent inhibition of alpha amylase activity was significantly (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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