Chronic Toxicity Studies of Aqueous Leaf Extract of Voacanga africana in Wistar Rats

Autor: Ighodaro, Igbe, Innih, Silvanus, Vincent Ogedengbe, Stephen, Amamina, Lucy
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Applied Sciences and Environmental Management; Vol 19, No 4 (2015); 639-646
ISSN: 1119-8362
Popis: Voacanga Africana stapf (Apocynaceae) leaves is being used in herbal medicine to treat leprosy, diarrhoea, generalized oedema and convulsion in children as an infant tonic and the present study was aimed at its toxicological evaluation in wistar rats. The sub-acute toxicity was evaluated after administering daily oral doses of Voacanga Africana stapf (100, 400 and 800 mg/kg) for 28 days after which the effect on anthropometric, haematological and histopathological parameters were assessed. There was a significant reduction (p
Databáze: OpenAIRE