In vivo
| Autor: | Nkanu, Etah Etah, Jeje, Sikirullai Olatunde, Ikpi, Daniel Ewa, Ujong, Gabriel Otu |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | International Journal of Biological and Chemical Sciences; Vol 10, No 4 (2016); 1573-1579 |
| ISSN: | 1991-8631 1997-342X |
| Popis: | The effect of aqueous extract of Spondias mombin leaves extract on lipid peroxidation and antioxidant activity in alloxan induced diabetes was studied. Forty male albino Wistar rats (100-150 g body weight) were used. The rats were randomly selected into four groups containing 10 rats each. Group 1 was the control group and it was placed on normal rat chow. Group 2 was the Spondias mombin (spm) group placed on normal rat chow and given 250 mg/kg extract orally. Group 3 was the alloxan-induced diabetic (150 mg/kg) group (DM) and Group 4 was the diabetic group treated with 250 mg/kg extracts (Dm+spm). At the end of 30 days blood samples were collected by cardiac puncture and used for biochemical analysis. Results obtained revealed that blood glucose level in group 3 (Dm) was significantly higher (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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