The usefulness of the ferritin and soluble transferrin receptor /(log)ferritin index in identifying iron deficiency among blood donors

Autor: Nwagha, T.U., Okoye, H.C.
Jazyk: angličtina
Rok vydání: 2023
Zdroj: East African Medical Journal; Vol. 100 No. 3 (2023); 5687-5696
ISSN: 0012-835X
Popis: Objective: To evaluate whether screening donors for red cell and iron indices before donation are useful in identifying donors with iron deficiency Methods: The Hb, red cell indices, serum ferritin (s-ferritin), soluble transferrin receptor (sTfR), and the sTfR/(log)ferritin (sTfR-F) index were measured. Diagnostic efficiencies of the sTfR / log ferritin index (sTfR / F) and s-ferritin were evaluated by receiver operating characteristic curve (ROC) analysis. The Youden index was used to determine the cutoff levels. Result: About 4.4% and 67.8% had reduced iron stores when classified as sferritin
Databáze: OpenAIRE