Acute and subacute toxicities of defatted ethanolic extract of Moringa oleifera seed in albino rats

Autor: Olorundare, O. E, Bello, M. K, Biliaminu, S. A, Babatunde, A. S, Ibrahim, O. O. K, Njan, A. A
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: West African Journal of Pharmacology and Drug Research; Vol 30 (2015); 46-51
ISSN: 0303-691X
Popis: Moringa oleifera seeds are widely accepted as a nutritional supplement. The seeds are consumed and are sold on the shelf of nature, herbal shops, pharmacy and supermarkets. They are consumed as herbal remedy for various diseases. This study was designed to evaluate the acute and sub-acute toxicity of defatted ethanolic extract of Moringa oleifera seed (DESMOL) in albino rats using standard methods. The extract at 400, 800, 1600mg/kg caused no significant changes (P>0.05) in haematological parameters such as PCV, RBC, Hb, MCV, MCH, WBC, lymphocyte and platelet counts. In contrast, the extract, at 800 and 1600mg/kg caused significant changes in the levels of total protein (P
Databáze: OpenAIRE