Haemato-biochemical alterations in experimental Wistar rats exposed to pyrethroid-based mosquito coils and local mosquito repellants smoke
Autor: | Nafi’u, S. A, Sulaiman, K, Ibrahim, A. A, Habib, R.A |
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Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Biological and Environmental Sciences Journal for the Tropics; Vol. 20 No. 1 (2023); 52-63 |
ISSN: | 0794-9057 2645-3142 |
Popis: | This study assessed the sub-acute toxicity of inhaling pyrethroid–based mosquito coil smoke and locally made mosquito repellents on the haematological indices, liver and kidney enzymes in experimental wistar rats. Fifteen (15) rats with mean weight of 150.5 g were randomly divided into five (5) groups. Group I were considered as negative control while group II, III, IV and V were exposed to mosquito coil (super kill), mosquito incense stick (shooter), orange peels and Eucalyptus leaves respectively 8 h daily for 21 days. They were kept in fabricated fly wood cages of 45x70cm = 315 sqcm2, mean room temperature 27.6 °C and a relative humidity of about 40% with 12 h light/dark cycle. Laboratory analysis in blood samples were carried out using standard procedure. The results obtained indicated significant decrease in weight in all the experimental rats compared with control. Red blood Cells (RBCs) count, haemoglobin (Hb) concentrations and packed cell volume (PCV) of the experimental rats reduced significantly (p |
Databáze: | OpenAIRE |
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