| Autor: |
Babić Jordamović, Naida, Kojović, Tamara, Dogan, Serkan, Bešić, Larisa, Salihefendić, Lana, Konjhodžić, Rijad, Škaro, Vedrana, Projić, Petar, Hadžiavdić, Vesna, Ašić, Adna, Marjanović, Damir |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| DOI: |
10.3389/fgene.2021.671467 |
| Popis: |
Human Y-chromosomal haplogroups are an important tool used in population genetics and forensic genetics. A conventional method used for Y haplogroup assignment is based on a set of Y-SNP markers deployed, which exploits the low mutation rate nature of these markers. Y chromosome haplogroups can be successfully predicted from Y-STR markers using different software packages, and this method gained much attention recently due to its labor-, time- and cost-effectiveness. The present study was based on the analysis of a total of 480 adult male buccal swab samples collected from different regions of Bosnia and Herzegovina. Y haplogroup prediction was performed using Whit Athey's Haplogroup Predictor, based on haplotype data on 23 Y-STR markers contained within the PowerPlex® Y23 kit. The results revealed the existence of 14 different haplogroups, with I2a, R1a and E1b1b being the most prevalent with frequencies of 43.13%, 14.79% and 14.58%, respectively. Compared to the previously published studies on Bosnian-Herzegovinian population based on Y-SNP and Y-STR data, this study represents an upgrade of molecular genetic data with a significantly larger number of samples, thus offering more accurate results and higher probability of detecting rare haplogroups. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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