Therapeutic drug monitoring of mycophenolic acid in patients with kidney transplant

Autor: Puretić, Zvonimir, Granić, Paula, Bubić-Filipi, Ljubica, Lalić, Zdenka, Lovrić, Mila, Humar, Ines, Mustapić, Željka, Sertić, Jadranka, Kes, Petar
Přispěvatelé: Banfić H., Boban M., Francetić I., Klarica M., Mück-Šeler D., Pivac N., Sabolić I., Tvrdeić A., Župan G.
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Popis: Mycophenolate mofetil (MMF) is an immunosupressive drug used in prophylaxis of rejection of transplanted solid organs in combination with cyclosporine A (CyA) and steroids. It is metabolised in the liver to the active component mycophenolic acid (MPA), an irreversible noncompetitive inhibitor of cell enzime 5'-monophosphate (IMP)dehydrogenase. The aim of the study was...
Databáze: OpenAIRE