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Introduction Healthy men tend to have more muscle and less fat mass than women due to higher levels of testosterone. Active endocrine adipose tissue in obese males contributes to the circulating pool of estrogens which results in distribution of adipose tissue and higher fat percentage. Obese men have frequently obesity related hypogonadsim and lower basal metabolic rate. The aim of this investigation was to explore changes in body composition in obese men and women during the same body weight reduction program. Methods Data from 161 obese patients (40 men, 121 women), mean age 50 years (22-80), attending structural weight loss program were analysed. A 5-day program included daily consultations with a multidisciplinary healthcare team. At the baseline and after 6 months anthropometric values (height, weight, body mass index -BMI) as well as body composition (fat mass, muscle mass) were estimated. Basal testosterone level was estimated in males. Results Baseline mean values of body mass, BMI, fat mass and muscle mass were 125 kg (78-240), 44 kg/m² (30-82), 58 kg (25-120) and 63 kg (43-139) retrospectively. In follow up after 6 months mean values of body mass, BMI, fat mass and muscle mass were 118 kg (72-223), 41 kg/m² (27-82), 52 kg (17- 104) and 62 kg (43-129) retrospectively. Basal testosterone level was 8.5 nmol/l (7.6-16). T- test of paired samples showed significant decrease in body mass (p |
