Immune response on surgery in regional and general anaesthesia

Autor: Šakić, Livija, Bagatin, Dinko, Bagatin, Tomica, Šakić, Kata
Přispěvatelé: Suljević, Ismet
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Popis: Surgery induces release of neuroendocrine hormones, cytokines and acute phase proteins. Study was to assess the effect of spinal and general anaesthesia on serum concentration of pro-inflammatory and anti-inflammatory cytokines, and cytokines which are secreted by Th1 helper lymphocytes. Surgery-related postoperative release of the pro-inflammatory cytokine IL-6 was increased in patients after spinal and general anesthesia. In this study, increased levels of the typical Th1 cytokine IL-2 were found in patients anesthetized by general anesthesia compared to spinal anesthesia. Serum concentrations of other pro-inflammatory cytokines, anti-inflammatory cytokines and cytokines which are secreted by Th1 helper lymphocytes showed no statistical difference before and after surgery under general and spinal anesthesia.
Databáze: OpenAIRE