Povišeni kateholamini u posttraumatskom stresnom poremećaju mijenjaju cerebralnu hemodinamiku

Autor: Dikanović, M, Kadojić, D, Mihaljević, I, Japundžić, V, Kadojić, M
Přispěvatelé: Branko Vitale
Jazyk: angličtina
Rok vydání: 2006
Předmět:
Popis: Previous investigations indicated cerebral hemodynamic changes in terms of increased mean blood flow velocities (mBFV) detected with transcranial dopler ultrasonography (TCD) in patients (pts) with posttraumatic stress disorder (PTSD). The aim of this study was to determine correlation between level of stress hormones and cerebral hemodynamic changes in PTSD pts. We examined 50 pts with acute PTSD, aged between 30 and 50 years (yrs), as well as 50 healthy subjects similar ages as control group. On the first day after hospitalization TCD was done and the measures of vanilmandelic acid (VMA) in 24-hour urine (as metabolit of adrenalin and nor-adrenalin) were analyzed in PTSD pts. The same diagnostic procedures were repeated after in PTSD pts 21-day long psychiatric treatment and in control subjects. In the first analysis 34 PTSD pts had increased mBFV, 29 of them (85.26%) had increased level of VMA. After 21-day long psychiatric treatment 9 PTSD pts had increased mBFV and 8 of them (88.88%) had increased level of VMA. The difference between two measures was statistically significant (p
Databáze: OpenAIRE