| Autor: |
Crnogorac, Matija, Horvatić, Ivica, Torić, Luka, Kaćinari, Patricia, Durlen, Ivan, Jurić, Klara, Tišljar, Miroslav, Galešić Ljubanović, Danica, Galešić, Krešimir |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
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| Popis: |
INTRODUCTION: Plasma exchange treatment (PLEX) in ANCA associated vasculitis (AAV) is still debated in terms of indications, number of treatments needed and its effects on overall patient and renal survival. We present data from Croatian referral center. METHODS: 108 patients with ANCA associated vasculitis have been analyzed, 60 females (55, 6%) with median age of 61 (Interquartile ratio - IQR= 51-70) years. Patients were categorized according to clinical (microscopic polyangiitis = MPA, granulomatosis with polyangiitis = GPA and renal limited vasculitis = RLV), serological (MPO-ANCA, PR3-ANCA, MPO and PR3- ANCA, ANCA negative) and histopathological phenotypes (according to Berden et al. classification). All the patients had renal biopsy performed. We analyzed PLEX as predictor for combined outcome end-stage renal disease and death (ESRDD), ESRD alone, death alone and relapse rate. Survival univariate analysis was performed using Kaplan-Meier analysis and log-rank (Mantel-Cox) test. Variables that had p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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