| Autor: |
Kovač, Nataša, Mladić Batinica, Inga, Kukin, Dijana, Murselović, Tamara, Tonković Dinko |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Popis: |
Normal saline or 0.9% NaCl solution is the most commonly used intravenous fluid worldwide and its composition are 154 mmol Na+ and 154 mmol Cl- per litter with osmolarity of 308 mOsmol/L. That composition is not “normal” because plasma contains sodium in range between 137-146 mmol/L, and chloride in range between 98-106 mmol/L, with plasma osmolality of 280- 295 mOsmol/kg. Recently published data suggested detrimental effects of chloride rich fluids on renal blood flow and glomerular filtration rate, urine output and acute kidney injury. One alternative to saline solution is a buffered, balanced, crystalloid solution with an electrolyte composition similar to plasma and osmolarity between 286-295 mOsmol/L. Someone could indicate that such balanced solutions are not suitable for neurosurgical patients because of a possible impact on the brain oedema development. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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