| Autor: |
Crkvenac Gornik, K, Štingl, K, Grubić, Z, Tonković Ð, urišević, I, Letica1, L, Burek, M, Lasan, R, Mužinić, D, Begović D |
| Jazyk: |
angličtina |
| Rok vydání: |
2008 |
| Předmět: |
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| Popis: |
Due to its high polymorphism, the analysis of Short Tandem Repeat (STR) markers using the PCR method has become a widely applied technique in forensic individual identification, rapid detection of chromosome aneuploidies in prenatal and postnatal diagnosis and paternity testing. Until now a large number of autosomal and Y-chromosomal markers has been forensically evaluated and used for various purposes, but the application of X-chromosomal markers has played only a minor role in forensic practice so far. The X-STR loci (DXS9895, GATA172D05, DXS6810, DXS6803 and HPRT) were investigated in male (N=90) and female (N=93) population samples from Croatia. Samples were collected from randomly selected unrelated healthy individuals. No deviation from the Hardy-Weinberg equilibrium could be detected and allele frequencies showed similar distribution in male and female samples. With the exception of DXS6810 locus for which only 6 alleles were observed and PIC value lover than 0.75 was calculated, all other loci have demonstrated sufficient polymorphism and PIC value to be considered valuable in future forensic analyses. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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