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Purpose: To determine the 6-month effect of conventional (CXL30) and accelerated crosslinking with UVA intensity of 9mW/cm2 (CXL10) on corneal stability and visual function and to investigate whether there was a difference in ABCD grading system parameters regarding the two procedures. Setting: Prospective study. Methods: Twenty-seven eyes of 25 patients with a documented diagnosis of keratoconus (KN) progression defined by the instructions from the Global Consensus on Keratoconus and Ectatic Diseases were included. Patients were selected to undergo either CXL 30 or CXL 10 procedure. After epithelial debridement, soaking the cornea with riboflavin 0.1%/hydroxypropyl methylcellulose 1.1% for 10 min. at 2-minute intervals, the surgeon decided to proceed with UVA irradiance of 3mW/cm2 or 9mW/cm2 . At the baseline visit and the follow-up visits after one month (mo.) (V1), three (V2), and six mo. (V3) postoperatively, all the patients underwent complete ophthalmic examination, including uncorrected visual acuity (UDVA), best- corrected visual acuity (BCVA), and corneal tomography (Pentacam HR ; Oculus, Wetzlar Inc, Germany). Results: In the CXL 30 group, all the parameters from ABCD grading system significantly changed from baseline visit to V3 ; parameter A decreased (2.5 vs. 2.6 vs. 2.4 vs. 2.5, p= 0, 048), B increased (4.66 vs. 4.54 vs. 5.03 vs. 4.99, p=0.01), C increased (1.52 vs. 2.09 vs. 2.36 vs. 2.14, p |
