Vagus Nerve Stimulation in Patients with Rheumatoid Arthritis: 24 Month Safety and Efficacy

Autor: Koopman, FA, Musters, A, Backer, MMJ, Gerlag, D, Miljko, S, Grazio, S, Sokolovic, S, Levine, Y, Chernoff, D, de Vries, N, Tak, PP
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Popis: The data presented here demonstrate that VNS in subjects with RA is associated with a substantial reduction in disease activity that is sustained for 24 months without untoward safety signals. Further, the data suggest that biological DMARDs may be initiated safely in combination with VNS treatment, though this requires validation in larger cohorts. These results support additional development of VNS devices as an alternative therapeutic approach for RA treatment, which potentially can safely be combined with biologic DMARDs.
Databáze: OpenAIRE