| Autor: |
Čoklo, Miran, Dolanc, Ivan, Carić, Tonko, Brozović Krijan, Antonija, Bočkor, Luka, Missoni, Saša |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Popis: |
The exposome concept was initiated within the field of epidemiology in 2005 to encompass “the totality of human environmental exposures from conception onwards, complementing the genome”. In the context of birth cohort studies and as- early-as-possible complex disease’ pre-vention, our focus is on the influence of maternal exposome on the offspring early growth and development as well as health outcomes in adulthood. As an example on how birth cohort can be used as a pow-erfull tool in exposing the transgenerational propagation of maternal exposome effects, we are presenting data of 150 mother-child dyads collected within the longitudinal CRIBS study focusing on relationships between maternal (such as physical activity, nutritional and lifestyle habits) and child parameters (early growth and development). Also, additional strategies regarding toxicological burden and epigenetic modifications (e.g. glycosylation) will be proposed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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