| Autor: |
Huguet, J. M., Ferrer-Barceló, L., Suárez, P., Tepes, B., Bordin, D., Leja, M., Babayeva, G., Lerang, F., Tonkić, Ante, Simsek, H., Kunovský, L., Gasbarrini, A., Buzas, G. M., Phull, P., Venerito, M., Puig, I., Nyssen, O. P., Mégraud, F., O’Morain, C., Gisbert, J. P. |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Popis: |
Objective: The adherence to Helicobacter pylori eradication treatment is a cornerstone for achieving an adequate treatment efficacy. The objective of the study was to determine which factors could influence on the compliance of treatments. Materials and Methods: Systematic prospective non- interventional registry (Hp- EuReg) of the clinical practice of European gastroenterologists. Compliance was adequate: >90% drug intake. Data collected until September 2021 at AEG-REDCap e- CRFand was subject to quality control. Modified intention-to-treat (mITT) analyses were performed. The multivariate analysis evaluated the factors associated with the effectiveness of the treatments and the compliance. Results: Of the 38, 698 records, 646 (1.7%) did not have adequate compliance. There was a higher non- compliance rate in patients prescribed with longer therapies (10-, 14-days), rescue treatment, with uninvestigated/functional dyspepsia, and reporting adverse events. Non- adherence was lower in first- line as compared to rescue treatment (1.5% vs. 2.2% ; p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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