| Autor: |
Karanović, Sandra, Fištrek Prlić, Margareta, Kos, Jelena, Premužić, Vedran, Abramović Barić, Mirta, Matijević, Vesna, Fucek, Mirjana, Vrdoljak, Ana, Cvitković, Ante, Leko, Ninoslav, Bitunjac, Milan, Laganović, Mario, Jelaković, Bojan |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
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| Popis: |
Introduction and Aims:Our aim was to analyse kidney function in prehypertensives comparing to subjects with optimal blood pressure and patients with untreated stage 1 hypertension. Methods:Out of 2489 subjects enrolled in Croatian rural study, 693 were eligible for further analysis. Exclusion criteria were antihypertensive treatment, hipertension stage 2, 3 and isolated systolic hypertension, diabetes mellitus, pregnancy, chronic terminal diseases, dementia, immobility and missing data. Blood pressure (BP) was measured following the ESH guidelines. Antropomietric measurements (height, weight) were determined. Fasting blood was analysed for serum creatinine. Urine was analysed for alpha1microglobulin, albumin, creatinine, sodium and potassium. Abbreviated MDRD formula was used to estimate glomerular filtration rate (eGFR). Albumin to creatinine ratio (ACR), alpha1 microglobin to creatinine ratio (alpha1CR) and sodium to potassium ratio (S/P ratio) were determined. Renal ultrasound was performed assesing longitudinal and transversal diameters and parenchimal thickness. Subjects were divided in three groups: optimal BP ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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