Autor: |
Gudelj, Martina, Srzentić, Sunčica, Bošković, Perica |
Přispěvatelé: |
Marković, Dean, Meštrović, Ernest, Namjesnik, Danijel, Tomašić, Vesna |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Popis: |
Micellar systems are colloids with various applications in different branches of industry such as cosmetic, petrochemical, pharmaceutical or food industry. Micelles can be used as nanocarriers of poorly water-soluble substances. This property is often used for drug delivery in medical treatments. Micelle formation is a complex process where multiple interactions take place, but most important are hydrophobic interactions. Propane-1, 2-diol (PG) is a substance commonly used as a food additive while benzyldodecyldimethylammonium (benzododecinium) bromide is quaternary ammonium salt used as preservative and antiseptic in pharmaceutical products. The latter is highly soluble in water and acts like cationic surfactant in aqueous solutions. The nature of the additive(PG) influences the micellar structure and properties of benzododecinium bromide. When increasing the mass fraction of propane-1, 2-diol in binary mixtures, the critical micelle concentration (CMC) values increase because the polarity of water is greater than that of the PG, the polarity of the system decreases with increasing PG mass fraction, and the repulsive electrical force of the ionic group is strengthened. Consequently, micelle formation becomes more difficult, which results in increasing CMC values. Increasing the temperature will increase the CMC for every mass fraction PG-water mixture. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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