| Autor: |
Kuna, Lucija, Petrović, Ana, Omanović Kolarić, Tea, Roguljić, Hrvoje, Sikora, Renata, Smolić, Robert, Včev, Aleksandar, Smolić, Martina |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Popis: |
The tooth derived from oral ectoderm is highly mineralized organ developed through epitheliummesenchyme interactions providing significant system for elucidating the molecular mechanisms of organogenesis. The cells used in tooth and bone development may be provided in the form of an immature intact matrix-organ culture, derived from tissues such as primary cultures or they may have been produced from tumor cells enabling standardized studies. Recently, there has been rising interest in epithelial cell tissue culture, especially oral mucosa and its application utilizing in vitro cell culture in dental research. Nevertheless, the research on tooth development is limited, considering epithelial stem cells are difficult to obtain and maintain. However, induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs) could be good alternative choices in understanding the functional roles in tissue engineering of teeth. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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