Autor: |
Škrtić, Anita, Mrzljak, Anna, Gašparov, Slavko, Čolić Cvrlje, Vesna, Naumovski Mihalić Slavica, Škegro, Dinko, Filipec Kanižaj Tajana, Guštin, Denis, Jadrijević, Stipislav, Kocman, Branislav |
Jazyk: |
angličtina |
Rok vydání: |
2011 |
Předmět: |
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Popis: |
Cytokeratin (CK) 10 is associated with invasiveness of hepatocellular carcinoma(HCC). Expression of CK7 and CK19 in HCC suggests worse prognosis based on a hihger HCC recurrence rate in in patients with CK overexpression after liver transplantation (LTx). The most frequently mutated genes in HCC are p53 and beta-Catenin. The aim of this study was to assess the occurrence of CK 7(10/19 and beta Catenin, alone or in combination, in comparison with FISH analysis of 17p13.1, clinico-pathological features and overall survival in HCC transplanted patients. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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