| Autor: |
Paladin-Pezo, S., Drašković, Milan, Naletilić, D., Šepić Grahovac, Dubravka, Bielen, Ivan, Hajnšek-Propadalo, Sanja, Poljaković, Zdravka, Hrabrić, Krešimir, Bošnjak, I., Vitas, Marija, Stanušić, K., Detoni, Josip, Sušak, R., Štetić, Viktor, Antonelli, Licia, Škarpa-Prpić, Ingrid, Ivanuša, Z., Krmpotić, Pavao, Dubroja, Ivan, Planjar, M., Sporiš, Davor, Plavec, Davor |
| Jazyk: |
angličtina |
| Rok vydání: |
2002 |
| Předmět: |
|
| Popis: |
Epilepsy and drugs used in its treatment can have significant impact on the patient’ s life. Because of its unique mechanism of action, Lamictal does not impair development of cognitive function and causes less central nervous system side effects. The aim of this multicentre prospective follow-up study was to assess the effect of 4-month Lamictal therapy on the quality of life modification in epileptic patients. The secondary aim of the study was to assess the patient’ s satisfaction with the treatment. The study included 63 patients of both sexes (30 men) older than 18 years, with the diagnosis of epilepsy, who had not been treated with Lamictal and had experienced at least one episode of epileptic seizure during the preceding year. Quality of life was evaluated by a standardized questionnaire for quality of life assessment in epileptics, QOLIE 31, distributed on the first visit when Lamictal was introduced, and 4 months after its introduction. Statistical analysis was done by use of t-test for dependent samples to compare the quality of life before and 4 months of therapy introduction, and analysis of variance for independent variables. At 4 months of Lamictal therapy, considerable improvement in the quality of life was recorded on the basis of total score(SD) (60.4[17.0]:50.3[19.7] ; p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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