| Popis: |
Recreational SCUBA (rSCUBA) diving is a specific type of underwater activity preformed in extreme environmental conditions. However, information on molecular events underlying (patho)physiological events that follow exposure to such conditions is still largely unexplored. To contribute to better understanding cardiac and immune system adaptation mechanisms triggered by repeated rSCUBA diving we measured copeptin, IgA, IgG, and IgM, complement components C3 and C4, and differential blood count parameters, including neutrophiltolymphocyte ratio (NLR), Nglycosylation of IgG and total plasma proteins (TPP), as well as cellfree DNA in blood samples of fourteen recreational male divers who performed five dives, one per week, on the depth 2030 m for 30 min, after nondive period of 5 months. Changes in measured parameters suggested that first dive triggered stress response that was abolished with repetition of diving since its beneficial effects on cardiac system (copeptin level) and immune status (NLR, immunoglobulins level, as well as IgG and TPP Nglycosylation pattern towards antiinflammatory status) were observed after the following dives. In conclusion, rSCUBA diving practiced on a regular basis induce cardiac adaptive response and promotes anti inflammatory status of the organism thus conferring cardioprotection as well as multiple health benefits. |
