| Autor: |
Milne, A.A., Murphy, W.G., Reading, S.J., Ruckley, C.V. |
| Zdroj: |
European Journal of Vascular and Endovascular Surgery; July 1995, Vol. 10 Issue: 1 p91-94, 4p |
| Abstrakt: |
Objectives:: To determine whether topical fibrin sealant reduced suture line bleeding during carotid endarterectomy with polytetrafluoroethylene (PTFE) patch closure. Design:: Prospective randomised non-blinded control trial. Setting:: Regional vascular surgery unit. Materials:: Seventeen patients undergoing carotid endarterectomy were randomised either to receive fibrin sealant as a topical haemostatic agent at the arteriotomy suture line or to act as control. Outcome measures:: Time taken to achieve haemostasis at the suture line. Intraoperative blood loss. Total operative time. Results:: The median time to achieve haemostasis was 5.5 min (range 4-31 min) in the treatment group and 19 min (range 10-47 min) in the control group. This difference was statistically significant p < 0.005 by Mann-Whitney test. There was no statistical difference in total operative time. Operative blood loss was lower in the treatment group (median 420ml, range 300-500ml) than in the control group (median 550ml, range 350-1200ml) but this difference was not statistically significant. One patient in the control group suffered a perioperative thrombo-embolic event. Conclusion:: Fibrin sealant is an effective topical haemostatic agent for arteriotomy suture lines involving PTFE material. |
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