| Autor: |
T. Stanton, David, J. Madhav, Prakash, J. Wilson, Larry, W. Morris, Timothy, M. Hershberger, Paul, N. Parker, Christian |
| Zdroj: |
Journal of Chemical Information and Modeling; January 2004, Vol. 44 Issue: 1 p221-229, 9p |
| Abstrakt: |
A set of compounds consisting of a new and diverse collection of biarylamides was examined using quantitative structure−activity relationship techniques for the purpose of developing a model to describe inhibition of gram-positive bacterial growth (minimum inhibition concentration). The model was sought in order to obtain insight for designing new molecules. A detailed analysis of the underlying structure−activity relationship helped provide insight concerning which structural features of the molecules modulated the activity of the compounds against gram-positive organisms. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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