Chemical Transformation of Prostaglandin-A2:  A Novel Series of C-10 Halogenated, C-12 Hydroxylated Prostaglandin-A2Analogues

Autor: S. Ratnayake, Anokha, S. Bugni, Tim, A. Veltri, Charles, J. Skalicky, Jack, M. Ireland, Chris
Zdroj: Organic Letters; May 2006, Vol. 8 Issue: 10 p2171-2174, 4p
Abstrakt: Synthesis of a novel class of C-10 halogenated and C-12 oxygenated prostaglandin-A2derivatives (6a−6c) has been accomplished. (15S)-Prostaglandin-A2(1), from the gorgonian Plexaura homomalla, served as the starting material for the synthesis. The absolute configuration was determined using NMR.
Databáze: Supplemental Index