EXPERIENCE WITH LYOPHILIZED HUMAN DURA MATER FOR URETHRAL STRICTURES

Autor: VILLAVICENCIO MAVRICH, H., PARADA MORENO, R., CAPARROS SARIOL, J., RUBIO BRIONES, J., ROSALES BORDES, A., VICENTE RODRIGUEZ, J.
Zdroj: The Journal of Urology; October 1998, Vol. 160 Issue: 4 p1310-1311, 2p
Abstrakt: PurposeWe report our results using lyophilized human dura mater for urethral strictures.Materials and MethodsThe results of 131 urethroplasties using lyophilized human dura mater grafts were reviewed. The etiology of the stricture was unknown in most cases and 44.3% had not been previously treated. Mean stricture length was 10 cm. A dura mater patch was used in 124 cases and tubular graft in 7.ResultsAverage followup was 56.6 months. The overall complication rate during the first month was 16.3%. At 6 months the graft failed in 2 cases and 25.2% had stricture recurrence. Good results were obtained in the longer term in 41.1% of cases, with a high recurrence rate and malignancy in 4 cases (3.2%) which required penectomy.ConclusionsDespite being a biologically well tolerated material, lyophilized human dura mater is not good for urethral strictures because of the high number of relapses and possibility of malignancy.
Databáze: Supplemental Index