| Autor: |
Antsypovitch, Sergei I., Oretskaya, Tat'yana S. |
| Zdroj: |
Russian Chemical Reviews; April 1998, Vol. 67 Issue: 3 p245-262, 18p |
| Abstrakt: |
Data on the methods employed for cross-linking of DNA strands and for the synthesis of oligonucleotide duplexes with cross-links between strands are summarised. Existing methods are systematised; their advantages and drawbacks are discussed. The examples of applications of DNA duplexes with covalently cross-linked chains for the study of proteinnucleic acid recognition and mechanisms of action of nucleic acid-binding proteins for gaining information about the spatial structure of nucleic acids, and for the solution of other problems of molecular biology are given. The bibliography includes 131 references. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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