Multiple Fiber Laser-Induced Thermotherapy for Ablation of Large Intrahepatic Tumors

Autor: Veenendaal, Liesbeth M., Jager, Arjan de, Stapper, Gerard, Rinkes, Inne H.M. Borel, Hillegersberg, Richard van
Zdroj: Photomedicine and Laser Surgery; February 2006, Vol. 24 Issue: 1 p3-9, 7p
Abstrakt: Objective: The aim of this study was to test three techniques used simultaneously to increase lesion size. Background Data: Laser-induced thermotherapy (LITT) is a method of local tumor ablation, which may prolong survival in patients with unresectable liver metastases. The main limitation has been the production of lesions with sufficient tumor-free margin. Methods: LITT treatment was performed with water-cooled, multiple fiber application and hepatic blood flow occlusion in six patients with unresectable intrahepatic metastases. Response was measured by computed tomography scan. Results: In all patients, tumors were effectively ablated. In two patients with colorectal metastases, lesions up to 8.6 cm could be created. Conclusion: The use of watercooled multiple fiber application and hepatic inflow occlusion makes LITT an effective ablative method, expanding the treatment options for patients with large intrahepatic masses.
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