Effects of Postprandial Administration of Insulin on Food Intake by the White Rat and the Mechanism of Appetite for Energy (first published in French in 1956)

Autor: LE MAGNEN, JACQUES
Zdroj: Appetite; August 1999, Vol. 33 Issue: 1 p8-13, 6p
Abstrakt: (1) Injection of insulin (5 or 10 Units/kg b.w.) immediately following a 30-min period of access to odourized food each day, repeated over 10–20 days, progressively induced a reduction in appetite for the food offered during this meal. (2) This reduction in appetite for that food was observed whether it was presented separately from or simultaneously with another food which differed only in the added odour (3) Insulin administration (10 U/kg) after a meal resulted in the maintenance of a residual state of hunger which eventually manifested itself in a resumption of ingestion. (4) These observations are interpreted as evidence of, on the one hand, the post-ingestive activity of food on the internal hunger stimulus in appetite conditioning and, on the other hand, of the role of food odour as an external stimulus of the conditioned ingestive reflexes.
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