| Autor: |
Anies, Claude, Billot, Laurent, Lallemand, Jean-Yves, Pancrazi, Ange |
| Zdroj: |
Tetrahedron Letters; October 1995, Vol. 36 Issue: 40 p7247-7250, 4p |
| Abstrakt: |
In a synthetic approach to forskolin 1, a 6-endo-trig radical cyclisation was performed on propargylic derivative 12 to furnish in 60% yield compound 17 which contains the A-B ring system of forskolin. In the same way yn-one 14 submitted to Bu3SnH gave the expected cyclised product 19 in 55% yield. A particular 5-exo-dig cyclisation took place, leading to compound 18 in 10% yield, when silylated propargylic alcohol 13 was treated under the same conditions. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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