Application of the Elbs persulfate oxidation to the preparation of 5-hydroxypyrimidines
Autor: | Hurst, DT |
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Zdroj: | Australian Journal of Chemistry; 1983, Vol. 36 Issue: 6 p1285-1289, 5p |
Abstrakt: | The use of potassium persulfate in cold sodium hydroxide solution has been shown to give the pyrimidin-5-yl hydrogen sulfates in cases where the pyrimidine has at least two electron-releasing groups in the 2,4 or 6 positions. However, the reaction has been unsuccessful in a number of cases. The pyrimidin-5-yl hydrogen sulfates are hydrolysed to the corresponding 5-hydroxypyrimidines by hydrochloric acid. |
Databáze: | Supplemental Index |
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