Application of the Elbs persulfate oxidation to the preparation of 5-hydroxypyrimidines

Autor: Hurst, DT
Zdroj: Australian Journal of Chemistry; 1983, Vol. 36 Issue: 6 p1285-1289, 5p
Abstrakt: The use of potassium persulfate in cold sodium hydroxide solution has been shown to give the pyrimidin-5-yl hydrogen sulfates in cases where the pyrimidine has at least two electron-releasing groups in the 2,4 or 6 positions. However, the reaction has been unsuccessful in a number of cases. The pyrimidin-5-yl hydrogen sulfates are hydrolysed to the corresponding 5-hydroxypyrimidines by hydrochloric acid.
Databáze: Supplemental Index