How Methionyl-tRNA Synthetase Creates its Amino Acid Recognition Pocket upon l-Methionine Binding

Autor: Serre, Laurence, Verdon, Grégory, Choinowski, Thomas, Hervouet, Nadège, Risler, Jean-Loup, Zelwer, Charles
Zdroj: JMB Online (Journal of Molecular Biology); March 2, 2001, Vol. 306 Issue: 4 p863-876, 14p
Abstrakt: Amino acid selection by aminoacyl-tRNA synthetases requires efficient mechanisms to avoid incorrect charging of the cognate tRNAs. A proofreading mechanism prevents Escherichia coli methionyl-tRNA synthetase (EcMet-RS) from activating in vivo
Databáze: Supplemental Index