| Autor: |
Chordia, Mahendra D., Gharpure, Milind M., Kingston, David G.I. |
| Zdroj: |
Tetrahedron; November 1995, Vol. 51 Issue: 47 p12963-12970, 8p |
| Abstrakt: |
Two facile B ring cleavage reactions of taxoids related to paclitaxel are reported. Treatment of a 13-chlorobaccatin with azide ion led to cleavage of the C-10/C-11 bond and formation of a hemiketal product. Treatment of a protected 2-debenzoyl paclitaxel with MnO2 yielded a ketoaldehyde in which the C-1/C-2 bond had been cleaved and the side chain had been eliminated. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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