Autor: |
Green, D. E., Ferreira, C. L., Stick, R. V., Patrick, B. O., Adam, M. J., Orvig, C. |
Zdroj: |
Bioconjugate Chemistry; November 2005, Vol. 16 Issue: 6 p1597-1609, 13p |
Abstrakt: |
Gallium and indium complexes with pendant carbohydrates have been prepared and examined for their potential as radiopharmaceuticals. Carbohydrate-bearing 3-hydroxy-4-pyridinone ligand precursors and their tris(ligand)gallium(III) and -indium(III) complexes were synthesized and characterized by mass spectrometry, elemental analysis, and 1H and 13C NMR spectroscopy, and in the case of one intermediate, by X-ray crystallography. With three equivalents of ligand, neutral complexes formed with the bidentate hydroxypyridinone moiety complexing the gallium(III) and indium(III) metal centers. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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