| Autor: |
Laurent, Ulla B.G., Dahl, Lauritz B., Lilja, Kajsa |
| Zdroj: |
Experimental Eye Research; October 1993, Vol. 57 Issue: 4 p435-440, 6p |
| Abstrakt: |
Catabolism of hyaluronan was studied by injecting hyaluronan (Mr200000) labelled with [125I]tyramine cellobiose, ([125I]-TC), into the anterior chamber of the rabbit eye. After endocytosis [125I]-TC accumulates in cells, allowing localization of the site of catabolism. When 0·1 ml of the aqueous humour was replaced with an equal volume containing polymer in tracer quantities, 24% was recovered from the eye at 2 hr and 6·5% at 6 hr after injection. With replacement of 0·2 ml of aqueous humour 38% and 19%, respectively, were found within the eye at the same time points. Most of the radioactivity was found in the liver. If the tracer was mixed with Healon® the removal from the anterior chamber was delayed. |
| Databáze: |
Supplemental Index |
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