| Autor: |
Tsang, C.W., Leung, O.K., Lee, P.P.N., Pang, S.F. |
| Zdroj: |
Biochemical and Biophysical Research Communications; April 1995, Vol. 209 Issue: 3 p1132-1139, 8p |
| Abstrakt: |
The endogenous levels of 5-methoxyindole-3-acetic acid (5-MIAA) in quail pineal gland, retina and serum were determined by capillary column gas chromatography/mass spectrometry/selected ion monitoring using a deuterated internal standard and the N-pentafluoropropionyl-O-pentafluorobenzyl ester derivative. Diurnal rhythms of pineal and serum 5-MIAA with high levels at mid-light and low levels at mid-dark suggest a pineal origin of 5-MIAA in the blood. In contrast, retina displayed an opposite diurnal rhythm of 5-MIAA with high levels at night, suggesting that the biosyntheses of 5-MIAA in the quail pineal gland and retina were different. In vitro studies on incubation media indicated that both the pineal gland and retina are capable of synthesis/secretion of 5-MIAA. |
| Databáze: |
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