Perfluoroalkylated amphiphiles with a morpholinophosphate or a dimorpholinophosphate polar head group

Autor: M. Sadtler, Ve′ronique, Jeanneaux, François, Pierre Krafft, Marie, Rábai, József, G. Riess, Jean
Zdroj: New Journal of Chemistry; June 19, 1998, Vol. 22 Issue: 6 p609-613, 5p
Abstrakt: Some previously synthesized (perfluoroalkyl)alkyldimorpholinophosphates, CnF2n+1CmH2mOP(O)- [N(CH2CH2)2O]2, were found remarkably to stabilize heat sterilizable water-in-fluorocarbon reverse emulsions and to have a strong proclivity to self-aggregate into microtubular assemblies when dispersed in water. This series has now been extended in order to allow structure–property relationships to be established and product optimization to be achieved. A new series of even more fluorophilic compounds consisting in bis[(perfluoroalkyl)alkyl]monomorpholinophosphates, (CnF2n+1CmH2mO)2P(O)N(CH2CH2)2O, was also synthesized. Preliminary surfactant activity and biocompatibility data are presented and compared to data obtained with non-fluorinated analogues.
Databáze: Supplemental Index