Two-Stage Inversion-Recovery Experiments for Measurements of T1

Autor: Taitelbaum, H., Ferretti, J.A., Spencer, R.G.S., Weiss, G.H.
Zdroj: Journal of Magnetic Resonance - Series A; October 1993, Vol. 105 Issue: 1 p59-64, 6p
Abstrakt: A theory for the optimal design of experiments for measuring values of T1using a two-stage design is developed. It is shown that a useful strategy in such designs is to make a preliminary rough estimate of T1and use the second stage to produce a refinement of the preliminary results. When the initial uncertainty interval for T1is large, the two-stage design produces results much less sensitive to the value of the true T1than those obtainable from a single-stage design. This leads to a significant improvement in the precision of estimates of T1, and in circumstances that depend on the value of T1estimated in the first stage of the experiment, to a considerable saving in spectrometer time.
Databáze: Supplemental Index