| Autor: |
Aranaz, Alicia, Romero, Beatriz, Montero, Natalia, A´lvarez, Julio, Bezos, Javier, de Juan, Luci´a, Mateos, Ana, Domi´nguez, Lucas |
| Zdroj: |
Journal of Clinical Microbiology; November 2004, Vol. 42 Issue: 11 p5388-5391, 4p |
| Abstrakt: |
ABSTRACTSpoligotyping is a major tool for molecular typing of Mycobacterium tuberculosiscomplex organisms. For epidemiological purposes, strains are considered clonal only when their spoligotyping patterns are identical. We report a change in the spoligotyping profiles of truly isogenic strains (a clinical isolate and a subculture derived in the laboratory) caused by deletion of a direct variable repeat. Without the information about the relationship between them, a link between these strains would have gone unnoticed. Evolutionary events should be taken into account in the interpretation of spoligotyping results and in the design of databases. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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