babA2- and cagA-positive Helicobacter pylori strains are associated with duodenal ulcer and gastric carcinoma in Brazil.

Autor: Oliveira, Adriana Gonçalves, Santos, Adriana, Guerra, Juliana Becattini, Rocha, Gifone Aguiar, Rocha, Andreia Maria Camargos, Oliveira, Celso Affonso, Cabral, Mônica Maria Demas Alvares, Nogueira, Ana Margarida Miguel Ferreira, Queiroz, Dulciene Maria Magalhães
Zdroj: Journal of Clinical Microbiology; August 2003, Vol. 41 Issue: 8 p3964-6, 3p
Abstrakt: The babA2 and cagA genes were investigated in 208 Brazilian Helicobacter pylori strains. A strong association between babA2 and duodenal ulcer or gastric carcinoma was observed, even after adjusting for confounding factors, such as age, gender, and cagA status. cagA-positive strains were also independently associated with H. pylori-related diseases.
Databáze: Supplemental Index