Highly purified vitamin B2 presents a promising therapeutic strategy for sepsis and septic shock.

Autor: Toyosawa, Toshio, Suzuki, Mamoru, Kodama, Kohtarou, Araki, Seiichi
Zdroj: Infection and Immunity; March 2004, Vol. 72 Issue: 3 p1820-3, 4p
Abstrakt: Highly purified vitamin B2 (riboflavin 5'-sodium phosphate; purity > 97%) treatment by intravenous infusion at doses above those used clinically to treat vitamin B2 deficiency showed therapeutic effects in mice not only in cases of endotoxin- and exotoxin-induced shock but also in cases of gram-negative and gram-positive bacterial infection even after the toxemia had already begun.
Databáze: Supplemental Index