Autor: |
McGuire, Carolann, Chan, Weng C, Wakelin, Derek |
Zdroj: |
Infection and Immunity; December 2002, Vol. 70 Issue: 12 p7149-52, 4p |
Abstrakt: |
Mice were successfully immunized against the intestinal nematode Trichinella spiralis by intranasal administration of a 30-mer peptide antigen with cholera toxin B. Immunized mice developed antigen-specific serum immunoglobulin G1, intestinal immunoglobulin A, and a type 2-biased cytokine response. Intranasal immunization therefore generates the Th2-mediated responses required for immunity against intestinal parasites. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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