| Autor: |
Erwin, James L., DaSilva, Luis M., Bavari, Sina, Little, Stephen F., Friedlander, Arthur M., Chanh, Tran C. |
| Zdroj: |
Infection and Immunity; February 2001, Vol. 69 Issue: 2 p1175-1177, 3p |
| Abstrakt: |
ABSTRACTWe present evidence that Bacillus anthracislethal toxin (LT) suppresses rather than induces proinflammatory cytokine production in macrophages. Suppression is observed with extremely low levels of LT and involves inhibition of transcription of cytokine messenger RNA. Thus, LT may contribute to anthrax pathogenesis by suppressing the inflammatory response. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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