Urethral Cytokine and Immune Responses inChlamydia trachomatis-Infected Males

Autor: Pate, Mitchell S., Hedges, Spencer R., Sibley, Don A., Russell, Michael W., Hook, Edward W., Mestecky, Jiri
Zdroj: Infection and Immunity; November 2001, Vol. 69 Issue: 11 p7178-7181, 4p
Abstrakt: ABSTRACTPenile urethral swabs collected from PCR-confirmed Chlamydia trachomatis-infected, C. trachomatis-uninfected, and non-C. trachomatis-infected, nongonococcal urethritis-infected males were analyzed for cytokine, total immunoglobulin (Ig), and specific antibody levels by enzyme-linked immunosorbent assay. Differential cellular components of the swab transport medium were also enumerated for the same groups. Although low, the levels of C. trachomatis-specific IgA and IgG antibodies and interleukin 8 cytokine were significantly higher inC. trachomatis-infected individuals. There were no significant differences in the levels of seven additional cytokines evaluated.
Databáze: Supplemental Index