| Autor: |
Narum, D L, Ogun, S A, Thomas, A W, Holder, A A |
| Zdroj: |
Infection and Immunity; May 2000, Vol. 68 Issue: 5 p2899-906, 8p |
| Abstrakt: |
We have purified apical merozoite antigen 1 (AMA-1) from extracts of red blood cells infected with the rodent malaria parasite Plasmodium yoelii yoelii YM. When used to immunize mice, the protein induced a strong protective response against a challenge with the parasite. Monoclonal antibodies specific for P. yoelii yoelii AMA-1 were prepared, and one was very effective against the parasite on passive immunization. A second protein that appears to be located in the apical rhoptry organelles and associated with AMA-1 was identified. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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