| Autor: |
Hanson, M S, Patel, N K, Cassatt, D R, Ulbrandt, N D |
| Zdroj: |
Infection and Immunity; November 2000, Vol. 68 Issue: 11 p6457-60, 4p |
| Abstrakt: |
Mice immunized with either the predominantly vector-stage lipoprotein outer surface protein A (OspA) or the in vivo-expressed lipoprotein decorin binding protein A (DbpA) are protected against Borrelia burgdorferi challenge. DbpA-OspA combinations protected against 100-fold-higher challenge doses than did either single-antigen vaccine and conferred significant protection against heterologous B. burgdorferi, B. garinii, and B. afzelii isolates, suggesting that there is synergy between these two immunogens. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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