Autor: |
Matousek, M P, Nedrud, J G, Cieplak, W, Harding, C V |
Zdroj: |
Infection and Immunity; July 1998, Vol. 66 Issue: 7 p3480-4, 5p |
Abstrakt: |
Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT) were found to inhibit intracellular antigen processing. Processing was not inhibited by mutant LT with attenuated ADP-ribosyltransferase activity, CT B or LT B subunit, which enhanced presentation of preexisting cell surface peptide-class II major histocompatibility complex complexes. Inhibition of antigen processing correlated with A subunit ADP-ribosyltransferase activity. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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