Autor: |
Becker, S I, Wang, R, Hedstrom, R C, Aguiar, J C, Jones, T R, Hoffman, S L, Gardner, M J |
Zdroj: |
Infection and Immunity; July 1998, Vol. 66 Issue: 7 p3457-61, 5p |
Abstrakt: |
Immunization of mice with DNA vaccines encoding the full-length form and C and N termini of Plasmodium yoelii merozoite surface protein 1 provided partial protection against sporozoite challenge and resulted in boosting of antibody titers after challenge. In C57BL/6 mice, two DNA vaccines provided protection comparable to that of recombinant protein consisting of the C terminus in Freund's adjuvant. |
Databáze: |
Supplemental Index |
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